Laugier-Hunziker syndrome: an important differential diagnosis for Peutz-Jeghers syndrome

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Laugier-Hunziker syndrome: an important differential diagnosis for Peutz-Jeghers syndrome.

Laugier-Hunziker syndrome (LHS) is a rare sporadic disorder, which shares some dermatological features with Peutz-Jeghers syndrome (PJS). However, whereas PJS is associated with hamartomatous gastrointestinal polyposis and carries a high risk of malignancy justifying intensive screening protocols, LHS is known to be an entirely benign disease with no systemic manifestations, which requires pati...

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The Laugier-Hunziker syndrome.

We describe a 46-year-old Hispanic woman who was incidentally found to have hyperpigmentation of the oral mucosa and nails during a routine full body skin examination. The patient reported having these changes for years with no symptoms. A diagnosis of the Laugier-Hunziker syndrome (LHS) was made. LHS is an acquired, benign condition characterized by pigmentary skin changes involving the oral m...

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Laugier Hunziker syndrome.

Laugier-Hunziker syndrome is characterized by idiopathic mucocutaneous pigmentation that may be associated with longitudinal melanonychia. The significance of this condition is due to its inclusion in differential diagnoses of pigmentary disorders of the oral mucosa, especially Peutz-Jeghers syndrome.

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Laugier-Hunziker syndrome - Case report*

Laugier-Hunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. We present the case of a 63-year-old female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7-year history of hyperpigmentation in several fingernails. Laugier-Hunziker syndrome was diagnosed based on the clinical features...

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Hyperpigmentation in Laugier-Hunziker syndrome.

1402 CMAJ, September 6, 2011, 183(12) © 2011 Canadian Medical Association or its licensors A60-year-old nonsmoking Chinese woman presented with a 40-year history of progressive blackish pigmentation of her tongue, oral mucosa and lips (Figure 1A; Appendix 1, available at www.cmaj.ca /lookup /suppl/doi:10.1503/cmaj.110211/-/DC1). In addition, she had a 10-year history of longitudinal pigmented b...

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ژورنال

عنوان ژورنال: Journal of Medical Genetics

سال: 2003

ISSN: 1468-6244

DOI: 10.1136/jmg.40.6.e77